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Overview Obstetric infections remain an important and potentially preventable contributor to maternal and neonatal morbidity and mortality. Intraamniotic infection (IAI) is associated with 20% of all preterm births (PTBs) and 50% of extreme PTBs at 28 weeks of gestation or…
Open full size image Key Abbreviations Antigen presenting cells APC B-cell activating factor of the tumor necrosis factor family BAFF B-cell receptor BCR CC receptor CCR CCL5 chemokine (C-C motif) ligand 5 CCL5 cGMP-AMP synthase-stimulator of interferon genes cGAS-STING CXC…
Key Points The innate immune system uses fast, nonspecific methods of pathogen detection to prevent and control an initial infection and includes macrophages, NK cells, the complement system, and cytokines. Macrophages have critical scavenger functions that likely help to prevent…