Introduction Following Goldblatt’s innovative work defining the causal relationship between renovascular disease and hypertension in 1934, the surgical management of renovascular disease evolved through three eras: nephrectomy, open surgical correction, and finally renal artery angioplasty with or without stenting (…
Until the early 1960s, the pathophysiology and management of atherosclerotic renovascular disease focused solely on hypertension. However, current management of renal artery atherosclerosis considers the relationship between renal artery occlusive disease and renal insufficiency, a relationship recognized by the term…
Historical Background In 1937 Goldblatt demonstrated that renal artery constriction produced atrophy of the kidney and systemic hypertension in a canine model. His elegant experiments defined a causal relationship between renovascular disease and hypertension. Leadbetter and Burkland are credited with…