Introduction Histogenesis Stromal and sex cord–stromal tumors of the ovary constitute a diverse collection that is derived from the ovarian cortical stromal and hilar cells ( Fig. 27.1 ). These cells form during embryogenesis as condensations of subcoelomic mesenchyme, in…
Epithelial Tumors Tumor Origin, Terminology, and Classification This chapter addresses pelvic epithelial malignancies that are commonly held synonymous with “ovarian cancer.” To maintain consistency, the term ovarian will be used as a generic term but this category encompasses tumors that…
Overview The Precursor-Cancer Connection The concept of adenocarcinoma in situ (AIS) was first proposed in 1953 by Friedell and McKay on the basis of two cases of cervical adenocarcinoma that also appeared to contain a noninvasive precursor lesion. However, in…