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Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Introduction Chronic pruritus or itch, defined as present for more…

Key points Itch and pain are key symptoms of atopic dermatitis (AD) that significantly affect quality of life; various classes of treatment aim to reduce these symptoms. Nonpharmacologic and topical therapies are effective for mild or moderate itch or pain…