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5-Lipoxygenase-Activating Protein Inhibitors: Promising Drugs for Treating Acute and Chronic Neuroinflammation Following Brain Injury
Leukotrienes The 5-lipoxygenase (5-LO) pathway mediates the production of leukotrienes, a class of potent inflammatory lipid mediators made in leuko cytes that contain a conjugated triene as part of their structure. The biosynthesis of leukotrienes is under strict control (for…