K. van Leyen Archives - Clinical Tree

Physical Address

304 North Cardinal St.
Dorchester Center, MA 02124

Introduction Global cerebral ischemia (GCI) is a major factor in the high mortality following cardiac arrest, which causes around 300,000 fatalities per year in the United States. Among the survivors, most have lifelong cognitive deficits. To model GCI in animals,…

Eicosanoids in Cerebrovascular Diseases

Introduction Eicosanoids have long been known to participate in cerebrovascular injury, starting in the early 1970s . Eicosanoids are derivatives of the 20-carbon polyunsaturated fatty acid (PUFA) arachidonic acid (AA); the more generalized term for oxidized versions of PUFAs is…

Tag K. van Leyen

Animal Models: Global Ischemia

Eicosanoids in Cerebrovascular Diseases