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Tag Joseph W. Shega

How Should Medications Be Initiated and Titrated to Prevent and Treat Nausea and Vomiting in Clinical Situations Unrelated to Chemotherapy?

Introduction and Scope of the Problem Nausea, vomiting, and retching are common and distressing symptoms encountered in patients with advanced illness. Among patients with cancer, up to 70% report these symptoms. Patients with other advanced illnesses may also report these…

How Should Medications Be Initiated and Titrated to Reduce Acute and Delayed Nausea and Vomiting in the Setting of Chemotherapy?

Introduction and Scope of the Problem Chemotherapy-induced nausea and vomiting (CINV) remains one of the most unpleasant, distressing, and feared symptoms for cancer patients. Without sufficient antiemetic prophylaxis, 30% to more than 90% of patients experience CINV with moderately emetogenic…

What Medications Are Effective in Preventing and Relieving Constipation in the Setting of Opioid Use?

Introduction and Scope of the Problem Constipation resulting from opioid use, commonly referred to as opioid-related constipation, opioid-induced bowel dysfunction, or opioid-induced constipation, is one of the most distressing symptoms experienced by patients, especially those with advanced illness. The prevalence…