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Historical Perspective on Postmastectomy Radiation Therapy PMRT Prior to Systemic Therapy The use of postmastectomy radiation therapy (PMRT) for improvement of breast cancer–specific outcomes has long been a topic of intense interest within the field of oncology. Prior to the…
Summary of Key Points The hallmarks of radiobiology are the “4 Rs”: r epair, r eassortment, r eoxygenation, r epopulation. Radiation exerts its biologic effects by causing damage to DNA. The linear–quadratic model provides a convenient method to compare different…