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The clinical and laboratory features of the three most common hereditary bleeding disorders—hemophilia A (factor VIII deficiency), hemophilia B (factor IX deficiency), and von Willebrand disease (VWD)—are discussed in this chapter. Hemophilia A and hemophilia B are both caused by…
Introduction Before initiating the laboratory workup of any patient with a suspected defect of hemostasis, the hematologist must first verify that the patient has a clinical history, signs, and symptoms compatible with a bleeding disorder. This is not an easy…