As discussed in the preceding chapter, the stomach is an active reservoir that stores, grinds, and slowly dispenses partially digested food to the intestine for further digestion and absorption. Its main secretory function is the production of hydrochloric acid. Gastric…
30.1 Duodenal Chemosensing Patterns and Mucosal Defense Factors The identification of luminal chemosensors in the gastrointestinal (GI) tract has emerged in part from the de-orphanization and characterization of nutrient-sensing G protein-coupled receptors (GPCRs) in the most recent decade. Since luminal…
28.1 Introduction For centuries, it has been known that ingestion of foods rich in indigestible carbohydrates, sugars, bitter substances, and fats elicits specific cellular responses, such as releasing hormones that alter gastrointestinal (GI) function. It has been only in the…