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Cytogenetic and molecular analyses have provided pivotal biologic and clinical insights into pediatric neoplasia. It is increasingly evident that genetic assays of various types can provide essential diagnostic or prognostic information about pediatric solid tumors and hematologic malignancies ( Tables…

The practice of surgical pathology has relied traditionally on evaluation of the gross and microscopic features of tissue specimens, integrated with the clinical history and other laboratory data, to reach a definitive diagnosis, assign prognosis, and assist the clinician and…