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■ Introduction Acute leukemias of ambiguous lineage may be divided into acute undifferentiated leukemia (AUL) and mixed-phenotype acute leukemias (MPALs). AULs are leukemias with very primitive phenotypes that lack definitive lineage-specific antigens. MPAL encompasses rare blastic hematopoietic cell neoplasms that…
▪ Introduction Acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) constitute a biologic continuum of neoplastic lymphoid disorders characterized by the proliferation of immature (blast) cells of B-cell or T-cell lineage. For clinical purposes, an arbitrary cutoff has been used…