Introduction ∗ This is an abridged version of this topic in Chapter 6 of the 7 th edition of this text Tissue microarray (TMA) is a method used to evaluate numerous samples of tissue in a short time. First introduced…
Introduction The aim of this appendix is to include discussion and methodology from the chapters Lipids, Proteins, Nucleic Acids and Enzyme Histochemistry which were included in previous editions of this book. These technologies have largely been superseded in the modern…
Introduction This is a large group of compounds with the general formula C n (H 2 O) n . The role of carbohydrates in cellular metabolism has been known for many years but carbohydrates have more recently been implicated in…
Introduction During embryonic development, the ectoderm and endoderm are divided by a germ cell layer, the mesoderm or mesenchyme. The term mesenchyme comes from the Greek ‘mesos’ meaning middle and ‘enchyma’ meaning infusion. Connective tissues and muscle develop from the…
Introduction Hematoxylin and eosin (H&E) is the most widely used histological stain. It is simple to use, easy to automate and demonstrates different tissue structures clearly. Hematoxylin stains the cell nuclei blue-black, showing clear intranuclear detail, whilst eosin stains cell…
Acknowledgment We would like to thank all the previous contributors to this chapter for their scientific input and Dr Catherine Cannet for her review of the chapter for this edition and her updates. Introduction This chapter discusses the basics of…
Introduction This is an introduction to the theory of light microscopy. The subject is dealt with in more depth in the previous editions of this book and further information may be found in dedicated texts to the subject. The light…