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Abbreviations 4-HNE 4-hydroxynonenal 5-HT-R 5-HT receptor ASIC1 acid sensing ion channel 1 ASIC2 acid sensing ion channel 2 ASIC3 acid sensing ion channel 3 CGRP calcitonin gene-related peptide CNS central nervous system CRD colorectal balloon distension CVH chronic visceral hypersensitivity…