Tag J.K. Aronson MA DPhil MBChB FRCP HonFBPhS HonFFPM

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General information Etanercept is a dimeric fusion protein consisting of two recombinant p75 tumor necrosis factor receptors fused with the Fc portion of human IgG1. It inhibits the binding of tumor necrosis factor alfa to its receptor and thereby neutralizes…

General information Etamsylate (formerly also known as cyclonamine) is a synthetic water-soluble non-steroidal drug (diethylamine 2, 5-dihydroxybenzenesulphonate), which was shown many years ago to increase platelet adhesion to glass beads. Subsequent clinical studies in animals reported dose-related reduced blood loss…

General information Etamivan has actions similar to doxapram hydrochloride and has been used as a respiratory stimulant [ ], for example in patients with respiratory failure [ ], hypoventilation during thoracic surgery [ ], postsurgical respiratory depression [ ], perinatal…

General information Etacrynic acid (ethacrynic acid) is a loop diuretic with similar actions to furosemide and bumetanide. However, it causes more adverse reactions than other loop diuretics and offers no clear advantages. Organs and systems Sensory systems Etacrynic acid is…

General information For a complete account of the adverse effects of estrogens, consult the following monographs as well as this one: Diethylstilbestrol Hormonal contraceptives—emergency contraception Hormonal contraceptives—oral Hormone replacement therapy—estrogens Hormone replacement therapy—estrogens + androgens Hormone replacement therapy—estrogens + progestogens.…

See also Omeprazole ; Proton pump inhibitors General information Esomeprazole is the S-isomer of omeprazole. The pharmacology, pharmacokinetics, efficacy, and safety of esomeprazole have been reviewed [ ]. Esomeprazole produces acid control comparable to that of currently available proton pump…

See also Beta-adrenoceptor antagonists General information Esmolol is a β 1 -selective adrenoceptor antagonist with an extremely short half-life (about 10 minutes), because of extensive metabolism by esterases in blood, liver, and other tissues. Organs and systems You’re Reading a…

General information Erythropoietin is an endogenous glycosylated protein hormone that is produced mainly in the kidneys and stimulates the production of members of the erythroid series of blood cells. Epoetin is the name that has been given to recombinant forms,…

See also Macrolide antibiotics General information For some decades erythromycin was the only macrolide antibiotic available, but with the development of new macrolides with remarkable pharmacokinetic and safety features [ ], it has met fierce competition and has, at least…