General information Antithrombin III is a small glycoprotein anticoagulant that inactivates several enzymes of the coagulation system and accounts for most of the antithrombin activity in plasma and also inhibits other proteolytic enzymes. It circulates in the plasma and inactivates…
General information Antimony is a brittle, bluish-white, metallic element (symbol Sb; atomic no 51). The symbol Sb comes from the Latin word stibium. Antimony is found in such minerals as dyscrasite, jamesonite, kermesite, pyrargyrite, stephanite, tetrahedrite, and zinkenite. The Arabic…
See also individual agents General information Histamine is both a local hormone and a neurotransmitter in the central nervous system. It is synthesized in neurons and mast cells. There are H 1 , H 2 , and H 3 receptors…
See also Antifungal azoles [for systemic use] General Information All the topically used azoles can cause local irritation, burning, and, if used intravaginally, burning, swelling, and discomfort during micturition. There is cross-sensitivity between econazole, enilconazole, miconazole, and probably all other…
See also individual agents; Antifungal azoles and other antifungal drugs for topical use General information The antifungal azoles are a class of synthetic compounds that have one or more azole rings and a more or less complex side chain attached…
See also individual agents General information Some of the drugs that are used to treat epilepsy can be grouped into classes (carbamazepine and its analogue oxcarbazepine, barbiturates, hydantoins, benzodiazepines, and succinimides), while others (for example valproate, felbamate, gabapentin, levetiracetam, lamotrigine,…
General information Classification Drugs used in dysrhythmias can be classified in different ways, the usual classification being according to their effects on the cardiac action potential [ ], as shown in Table 1 . Table 1 Electrophysiological classification of antidysrhythmic…
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See also individual agents General information There are many anticholinergic drugs, some structurally related to atropine, others quaternary ammonium compounds or tertiary amines ( Table 1 ). Although many of these products are claimed to have superior efficacy, specificity, or…
See also Monoclonal antibodies General information BG9588 is an anti-CD40L antibody. The CD40–CD40L interaction plays a significant role in the production of autoantibodies and tissue injury in lupus nephritis [ ]. You’re Reading a Preview Become a Clinical Tree membership…