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Tag Jeremy L. Ramdial

Cytokine Release Syndrome Following CD19 Directed Chimeric Antigen Receptor T-Cell Therapy

Introduction T-cells genetically engineered to express a chimeric antigen receptor (CAR) that targets a specific tumor antigen have become a major clinical tool to treat several high-risk hematologic malignancies. Since the development of the first CAR T-cell in 1989, remarkable…

Transfusion Support During Hematopoietic Cell Transplantation

Blood products are essential during the peritransplant period. Patients receiving hematopoietic cell transplantation (HCT) require extensive transfusion support until appropriate platelet and red blood cell (RBC) engraftment ensures. The platelet lineage is considered engrafted when a patient’s platelet count is…