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Acknowledgments This work was partly supported by NIH grant U54 HD090259. Introduction Rapid and complex changes in physiology occur when the fetus transitions from an intrauterine to an extrauterine environment. From dependency on the maternal circulation via the placenta for…
Serious infections can occur during pregnancy and must be treated to prevent maternal and fetal adverse outcomes. While some anti-infectives have been studied in pregnancy, many agents have inadequate data available to evaluate safety, efficacy, and appropriate dosing, posing a…