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Acute Phase Response Stimuli of many kinds, including infection, trauma, hemorrhage, or ischemia, activate the innate immune system through binding of pathogen-associated molecular patterns (PAMPs) and/or danger-associated molecular patterns (DAMPs) to pattern-recognition receptors (PRRs) on the surface of neutrophils, monocytes,…
Fusobacteria are non–spore-forming, nonmotile, pleomorphic, gram-negative ( Fig. 193.1 ), obligate anaerobic bacilli that can cause a wide spectrum of human disease ranging from mild pharyngitis to sepsis, and these organisms are most notorious for causing septic thrombophlebitis of the…
Of the Haemophilus species, H. influenzae causes by far the most human disease. Several other members of this genus, however, cause clinical illness. These include H. influenzae biogroup aegyptius , H. ducreyi, H. parainfluenzae, H. pittmaniae, H. sputorum, H. haemolyticus,…