Bacterial contamination of blood components may result in septic transfusion reactions ( Chapter 67 ), which can be fatal. Platelet products, particularly those on day 4 or 5 of storage, are most commonly associated with these reactions because they are…
About 2%–5% of whole blood donors experience some form of reaction although most are mild vasovagal reactions and small hematomas. Reactions are more likely to occur in young (≤20 years old), low weight/blood volume, first-time, and female donors. Vasovagal reactions…
Physicians play a central role in blood centers with direct and indirect responsibilities. The physician’s role actively participates in the blood center activities, including collection, manufacturing, storage, and distribution of biologics (cellular therapies and blood components), and, in some cases,…