Tag Jean-Pierre Guignard

Acknowledgments We acknowledge with great sadness the passing of Dr. Michael Linshaw, the renowned pediatric nephrologist who contributed the “Concentration and Dilution of Urine” chapter to this textbook for several editions. He was a beloved teacher and mentor who enjoyed…

Introduction The production of urine begins with the formation of an ultrafiltrate of plasma by the glomerulus. The function of the tubule is to modify this ultrafiltrate to allow an efficient excretion of waste products and the retention of those…