Introduction Although epithelial neoplasms predominate in the tubal gut, a variety of mesenchymal neoplasms may originate from or secondarily involve the gastrointestinal (GI) tract. Given the rarity of these lesions and the fact that many have overlapping histological features, accurate…
Introduction Large bowel screening programs have been shown to substantially reduce the incidence of colorectal carcinoma by identifying and removing premalignant polyps. Increased use of colonoscopy has led to an increase in the number of polyps encountered in daily pathology…
The impact of diagnostic immunohistochemistry (IHC) for the surgical pathologist is legendary, and it is best appreciated when studying malignancies of unknown primary site. A cost-effective tool, IHC is performed in most hospital laboratories, is often automated, and provides for…
Acknowledgment We are grateful to Dr. Mark Wick, who was the author of this chapter in earlier editions and was responsible for much of the content in the sections on biology of antigens and antibodies. Overview Tumors of soft tissue…
Small Intestine Epithelial Tumors Adenoma Clinical Features. Adenomas of the small intestine are relatively uncommon, compared with adenomas of the large intestine. Around 80% arise in the periampullary duodenum. Duodenal adenomas occur over a wide age range (mean 60 years),…