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Summary of Key Points Incidence Bone metastasis is a major cause of (often prolonged) morbidity in persons with cancer. Bone metastasis is especially prevalent in persons with breast and prostatic cancers. Causes Disseminated tumor cells are attracted to vascular, osteoblastic,…
Research highlights Bone is the preferred site of metastasis in breast cancer, especially in ER/PR-positive tumors CDK4/6 inhibitors combined with aromatase inhibitors/fulvestrant prolong PFS including in patients with bone metastases In HER2-positive patients with bone metastases new combined therapies and…