Tag James W. Vardiman

Myelodysplastic/Myeloproliferative Neoplasms

The myelodysplastic/myeloproliferative neoplasms (MDS/MPNs) are clonal myeloid disorders that, at the time of initial diagnosis, have some clinical, laboratory, or morphologic features supporting the diagnosis of a myelodysplastic syndrome (MDS), such as persistent cytopenias and dysplasia involving one or more…

Myeloproliferative Neoplasms

Definition The myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders characterized by proliferation of cells of one or more of the myeloid lineages, erythroid, granulocytic, or megakaryocytic. Initially, the proliferation in the bone marrow is effective and associated with maturation of…