Editor's comment : This new chapter is included in recognition of the increasing power of informatics and data analysis that have become evident in the 21 st century. We are no longer constrained to examining tiny “slices of disease” or…
Editors' comment: This is a modified chapter since the fourth edition. When it was published in 2015, the editors had come to the realization that methods revealing the molecular biology of the trophoblast were likely to contribute in new ways…
Editor's comment: Preeclampsia–eclampsia is a leading cause of maternal mortality and morbidity. Eclampsia has decreased dramatically in the last several decades in high-resource countries, probably reflecting improvements in medical care rather than a change in the disease's natural history. Conversely,…
Editors ' comment: When Leon Chesley's Hypertensive Disorders in Pregnancy was initially published in 1978 , as now, hypertension complicating pregnancy was a major cause of fetal and maternal morbidity and death. Most of this morbidity was and remains associated…