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Acknowledgments Dr. Ibrahim is supported in part by the Dennis and Marilyn Barry Fellowship in Cardiology Research. Dr. Gaggin is supported in part by the Ruth and James Clark Fund for Cardiac Research Innovation. Dr. Januzzi is supported in part…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Heart Failure Definition and Epidemiology Heart failure (HF) is a complex clinical syndrome resulting from structural and functional impairment of ventricular filling or ejection of blood. While the clinical…