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Key Points 1 The 10 most frequent causes of acute drug-induced liver injury (DILI) in the prospective Drug-Induced Liver Injury Network (DILIN) are amoxicillin-clavulanic acid (amox-clav), isoniazid (INH), nitrofurantoin, sulfamethoxazole-trimethoprim (SMX-TMP), minocycline, cefazolin, azithromycin, ciprofloxacin, levofloxacin, and diclofenac. These 10…