Tag James B. Bussel MD

This chapter will focus on the acquired etiologies of neonatal thrombocytopenia as congenital and alloimmune thrombocytopenias are discussed in Chapter 93, Chapter 94 . Neonatal thrombocytopenia occurs in 1%–2% of healthy term neonates but is common in the neonatal intensive…

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is characterized by the presence of transient isolated neonatal thrombocytopenia secondary to maternal antibodies against paternally inherited antigens expressed on the fetal platelets. FNAIT is the most common cause of severe thrombocytopenia (<50,000/μL) in…