Physical Address

304 North Cardinal St.
Dorchester Center, MA 02124

Tag Jacob Raphael MD FAHA

Coagulation and Transfusion Management

Key Points 1. Clinical hemostasis reflects an integrated interplay between the coagulation system, the fibrinolytic system, platelets, and the vascular endothelium. 2. The coagulation cascade has four main components, namely the contact activation, the extrinsic, the intrinsic, and the common…

Coagulation Monitoring

Key Points 1. Monitoring the effect of heparin is done using the activated clotting time (ACT), a functional test of heparin anticoagulation. The ACT is susceptible to prolongation because of hypothermia and hemodilution and to reduction because of platelet activation.…