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Role of Stemness Factors in Neuroblastoma: Neuroblastoma Stem Cells, Tumor Microenvironment, and Chemoresistance
Cancer Stem Cells The cancer stem cell (CSC) paradigm is the idea that subpopulations of cancer cells exist within a tumor that has capabilities similar to a normal stem cell: self-renewal, multipotency, proliferation, and tumor maintenance . This concept that…