1. What is membranoproliferative glomerulonephritis (MPGN)? (MPGN) is a rare form of glomerular disease that occurs in both children and adults. It is characterized by a unique histopathologic feature, namely splitting of the glomerular basement membrane (GBM) with interposition of…
1. What is nephrotic syndrome? Nephrotic syndrome is one of the most rigidly defined entities in clinical medicine. The term is not a specific diagnosis, but instead represents a cluster of abnormal findings. Specifically, it is comprised of four distinct…
Terminology and Histopathology Minimal change disease (MCD) is a common cause of nephrotic syndrome (NS). Also known as lipoid nephrosis, nil disease, and minimal change nephropathy , the kidney histology on light microscopy in MCD is relatively normal and lacks…