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Introduction This chapter focuses principally on epithelial neoplasms of the vagina (soft tissue tumors are discussed in detail in Chapter 9 ). The most common lesions in the epithelial group are squamous, ranging from mild dysplasia to invasive squamous carcinomas.…

Introduction Both the anatomy and histology of the vagina vary throughout life. Traditionally, the vagina is divided into thirds—upper, middle, and lower—using pelvic, fascial, and muscular planes. The mucous membrane of the vagina is covered by a stratified, squamous, nonkeratinizing…

Introduction Pigmented lesions of the vulva are a concern to patients, their health care providers, and pathologists who interpret the histopathology. Gynecologists are particularly wary of pigmented lesions of the vulva—the prognosis for vulvar melanoma is poor because of the…

Introduction The clinician and pathologist must recognize benign cysts and adnexal lesions of the vulva to exclude more serious conditions and avoid misclassifying them as malignancies ( Table 5.1 ). They typically do not pose a diagnostic problem with the…

Introduction A variety of organisms can infect the female genital tract, accounting for considerable suffering and morbidity ( Table 4.1 ). Some, such as candidal infections, trichomoniasis, and bacterial vaginosis, are extremely common and may cause significant discomfort, but with…

Introduction Vulvodynia is defined as a chronic discomfort or pain, consisting of burning, stinging, irritation, and rawness on the vulva. It was once believed to be a rare condition, but is now known to affect millions of women. It can…

Introduction Diagnostic dermatopathology of the vulva is a field that may be practiced on a multitude of levels. Patients may be seen by gynecologists, family practitioners, internists, or dermatologists. The biopsy may be read by a dermatopathologist, gynecologic pathologist, or…