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Disorders of the immune system are diverse and range from mild to severe in their manifestations and impact on normal function. In this chapter, we review the physical findings and characteristic symptoms of children with hypersensitivity reactions and immune deficiencies,…
Infection and disease develop when the host immune system fails to protect adequately against potential pathogens. In individuals with an intact immune system, infection occurs in the setting of naïveté to the microbe and absence of or inadequate preexisting microbe-specific…