Tag Hermann Haller

Thrombotic microangiopathies

1. Define thrombotic microangiopathy. Thrombotic microangiopathy (TMA) is a pathologic description characterized by arteriole and capillary endothelial vessel wall damage that results in platelet activation, thrombosis, and damaged erythrocytes (schistocytes) leading to ischemia and organ failure. Several different clinical syndromes…