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Introduction Over the past half century, breast cancer management has evolved from primarily surgical therapy to a multidisciplinary approach including surgery, radiation therapy and systemic therapy. This shift is based on an increased understanding of invasive breast malignancy as a…
Over the past 40 years, new and advanced breast cancer multimodality treatments have resulted in improved median survival times for patients with metastatic breast cancer (MBC). Breast cancer most commonly metastasizes to bone, followed by lung, brain, and liver. Until…
Lobular Neoplasia Lobular neoplasia is the overarching nomenclature used to describe the spectrum of proliferative but noninfiltrative changes seen within the lobular units of the breast. Lobular neoplastic lesions include atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS),…