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Introduction Prehistoric and Historic Perspectives Wounds due to combat, hunting injuries, accidents, and thermal injuries have been the leading causes of death in humans for millennia, whereas prolonged survival of large full-thickness wounds is a recent phenomenon. Complex biological responses…
Introduction A large burn is not a simple injury but a very complicated disease. This statement, restated from its publication in 1840, holds true with additional force in 2016. Massive destruction of skin tissue by burns stimulates many complex reactions…