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Summary of Key Points Incidence The incidence of chronic myeloid leukemia (CML) is 1.5 in 10 5 , about 5000 cases per year in the United States; CML represents 15% of all leukemias. The prevalence of CML was 30,000 cases…
Introduction The genesis of human myeloid leukemia involves the deregulation of the differentiation and maturation programs of the hematopoietic myeloid lineage that originates from primitive stem cells with multilineage potential. Myeloid leukemias have been linked to the acquisition of chromosomal…