Tag H. Chabriat

CADASIL

Introduction The acronym CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is for an autosomal dominant inherited cerebral small-vessel disease responsible in adults for subcortical infarcts and leukoencephalopathy . Mutations in NOTCH3 gene on chromosome 19 are responsible…