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Introduction Gastric cancer remains an important cancer worldwide and is responsible for over 1 million new cases in 2020, and an estimated 769,000 deaths (equating to 1 in 13 deaths globally), ranking fifth for incidence and fourth for mortality globally.…

Introduction Gastric polyps are identified in up to 6.3% upper gastrointestinal (GI) endoscopic procedures. They may develop as a result of epithelial or stromal cell hyperplasia, inflammation, ectopia, or neoplasia. This chapter classifies gastric polyps according to the predominant cell…

Historical Perspective In 1947, at the dawn of gastroscopy, Rudolf Schindler deemed gastritis “one of the most debated diseases of the human body” and predicted that its significance would be discussed “for some time to come.” From the mid-1800s, when…

The surgical pathologist plays a key role in the diagnosis of gastrointestinal infection. Virtually all types of pathogenic microbes can cause gastrointestinal infection, so the diagnostic pathologist must be cognizant of their varied histologic manifestations and acquainted with the complex…

Esophagus Epithelial Tumors Squamous Cell Papilloma and Papillomatosis Clinical Features. Squamous cell papilloma may occur anywhere in the esophagus but is found most commonly in the lower third as a single, well-demarcated sessile intraluminal tumor, usually less than 1.5 cm in…