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Abstract Background Once thought of as a simple clonal expansion of abnormal cells, cancer is now recognized as a complex, multifactorial, and polygenic syndrome. Many cancer types have been reclassified due to new understanding of molecular-based phenotypes and tumor-host interactions.…

Abstract Background Nucleic acid techniques as applied to molecular diagnostics have enabled the laboratorian to modify, amplify, detect, discriminate, and sequence nucleic acids with levels of sensitivity and specificity unparalleled by other laboratory techniques. Molecular diagnostic techniques continue to produce…