Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease of unknown cause characterized by diffuse inflammation and fibrosis of intrahepatic and/or extrahepatic bile ducts and is strongly associated with inflammatory bowel disease (IBD). PSC is ultimately progressive, leading to…
Overview Liver transplantation (LT) is considered standard of care for select patients with hepatocellular carcinoma (HCC) arising in the setting of cirrhosis (see Chapter 108A ). The role of LT in treatment of other malignancies arising in the liver such…
Abbreviations ABC-2 Advanced Biliary Cancer 2 CCA cholangiocarcinoma CDK cell division kinase CI confidence interval COX-2 cyclooxygenase 2 CT computed tomography EBRT external-beam radiation therapy EGF epidermal growth factor EGFR epidermal growth factor receptor ERC endoscopic retrograde cholangiography EUS endoscopic…
Acknowledgment This work was supported by grants from the NIH DK59427 (G.J.G.) and K08CA236874 (S.H.R.). Support was also provided to Dr. Rizvi by a Pilot & Feasibility Award by the Center for Cell Signaling in Gastroenterology (P30DK084567), and an AGA…