Key Points The immediate mechanism of action of modern antidepressants (“immediate effects”) involves influencing the function of one or more monoamine neurotransmitter systems (serotonin, norepinephrine [noradrenaline], or dopamine). Influencing monoaminergic function has been shown to result in several changes in…
Overview A major depressive disorder (MDD) serious enough to warrant professional care affects approximately 16% of the general population during their life-time. Both the Epidemiological Catchment Area (ECA) study and the National Comorbidity Survey study have found that MDD is…
Key Points The immediate mechanism of action of modern antidepressants (“immediate effects”) involves influencing the function of one or more monoamine neurotransmitter systems (serotonin, norepinephrine [noradrenaline], or dopamine). Influencing monoaminergic function has been shown to result in several changes in…