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Tag Frederic T. Billings

Statins and the Kidney

Objectives This chapter will: 1. Review the mechanism of action, indications, biologic effects, and complications associated with statin treatment. 2. Discuss the role of statin treatment in chronic kidney disease patients. 3. Examine the evidence for statin use in patients…

Statins

Uses Incidence in USA: Estimated 20 million Primary indications include: Hyperlipidemia: HMG-CoA reductase inhibitors (statins) are powerful drugs for lowering LDL cholesterol concentrations, and certain statins—atorvastatin in high doses and rosuvastatin—increase concentrations of healthy HDL cholesterol. Primary and secondary prevention…