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The first use of limb amputation was as an implement of punishment or torture. Hippocrates is credited with performing the first amputation for therapeutic purposes. Well into the 20th century, toe or forefoot gangrene was associated with limb loss. Leland…
Historical Background In 1785 Hunter successfully ligated the popliteal artery of a coachman with a large popliteal aneurysm, relying on collateral circulation to maintain the viability of the limb. In 1916, while working at Johns Hopkins, Bertram Bernheim was the…