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Involvement of the CXCL12/CXCR4/CXCR7 Axis in Brain Metastases
Introduction Chemokines are a superfamily of small cytokines (8–12 kDa) with chemotactic properties. They bind to specific receptors and are involved in cell trafficking, activation and differentiation. More than 50 different chemokines have been identified and are classified into four…