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The etiology of neonatal renal failure encompasses both chronic conditions such as congenital defects of the kidney and urinary tract and acute insults such as hypoxia, ischemia, or drug toxicity leading to acute kidney injury (AKI) ( ). AKI in…
Acknowledgments The authors are supported by the following funding: PG: NICHD, Pediatric Scientist Development Program (PSDP) and K12-HD000850. FL: R01DK118140, R01DK107653. JC: R01DK110622, R01DK111861, U34DK117128. Introduction Glomerular endowment is highly variable in humans. Although each kidney contains approximately 1 million…