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Research highlights Treatment options for myeloma bone disease have increased during the last years. Denosumab is an RANKL inhibitor that has shown its noninferiority in SRE prevention compared to zoledronic acid. Denosumab may constitute a safer option for patients with…
Introduction Osteocytes are terminally differentiated cells of the osteoblast lineage. They are the most abundant cell type of the bone, representing 95% of all bone cells in skeletally mature adult bone tissue [ ]. Osteocytes are considered permanent residents of…