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Key Points Labor results in significant pain for many women that is individualized, dynamic, and unpredictable. Although the effects of obstetric analgesia and anesthesia on the fetus and neonate are typically benign, there is potential for adverse neonatal effects. During…
Key Points ▪ The normal physiologic changes of pregnancy begin in the first trimester, affect all organ systems, and alter pharmacokinetic and pharmacodynamic responses to many drugs commonly used in anesthesia. ▪ Maternal-fetal exchange of most drugs and other substances…