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Myelodysplastic Syndromes and Myeloproliferative Neoplasms in Children
Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) are a heterogeneous group of clonal stem cell disorders that result in ineffective hematopoiesis and an increased risk of developing acute myeloid leukemia (AML). Whereas in MDS ineffective hematopoiesis results in progressive cytopenias,…