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Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
Key Points CADASIL is a familial small artery disease responsible for migraine with aura, stroke, disability, and cognitive decline. The disease occurs during midadulthood. CADASIL is caused by mutations of NOTCH3 gene. CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts…